Enzymatic and mutational analyses of a class II 3',5'-cyclic nucleotide phosphodiesterase, PdeE, from Myxococcus xanthus.

نویسندگان

  • Yoshio Kimura
  • Masaaki Yoshimi
  • Goro Takata
چکیده

Myxococcus xanthus PdeE, an enzyme homologous to class II 3',5'-cyclic nucleotide phosphodiesterases, hydrolyzed cyclic AMP (cAMP) and cGMP with K(m) values of 12 μM and 25 μM, respectively. A pdeE mutant exhibited delays in fruiting body and spore formation compared with the wild type when cultured on starvation medium.

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عنوان ژورنال:
  • Journal of bacteriology

دوره 193 8  شماره 

صفحات  -

تاریخ انتشار 2011